Patients With SDB and Canadian Pharmacy
The studies in this section will deal with SDB in the form of snoring, UARS, and OSAS. Some of the studies chose to specifically differentiate these types of SDB and are noted with such designations herein.
In one study mentioned above, there was no correlation between upright, awake NR and the degree of SDB in patients referred for SDB. A second study measured NR in 36 patients with OSAS using basal anterior active rhinomanometry in both upright and supine positions, and found 7 of 36 patients with abnormal upright NR, 9 of 36 patients with a normal upright but abnormal supine NR, and 20 of 36 patients with normal NR in both positions.
Table 7—Studies Evaluating the Relationship Between Adult Allergic Rhinitis and SDB*
|Source/Year||Study Population||Diagnostic Method||Observation||Conclusion|
|Lavie/1981||14 patients (9 males)7 normal controls||Anamnesia about duration of disease, sneezing and nasal discharge, ENT examination; nasal smears for eosinophil count||PSG for 2 nights||During exacerbation of allergic rhinitis: periodic breathing and microarousals|
|McNicholas/1982||10 patients||Hypersensitivity to ragweed pollen (history, skin testing), excluded asthma, medications held||PSG for 2 nights: first duringpeak ragweed season (with symptoms), and 6 to 8 weeks later with no symptoms||During symptomatic phase of allergic rhinitis: higher NR, and increased obstructive apneas|
|Young/2001||911 patients||History of allergy, hay fever causing nasal congestion, on allergy||PSG, questionnaire: EDS, sleep history; rhinometry||Nighttime nasal obstruction associated with allergic rhinitis caused EDS, snoring, nonrestorative sleep. Those with nasal congestion associated with allergic rhinitis are 1.8 times more likely to have SDB|
|Craig/1998||20 patients||Positive skin test responses to perennial allergen||Nasal symptoms, subjective sleep, EDS during double-blind, placebo-controlled trial of nasal steroid vs placebo||Nasal congestion and subjective sleep improved in those treated with nasal steroid and not with placebo|
*See Table 6 for expansion of abbreviations.